DeCS Server - List Exact Term

Search on:	COMPLEMENT COMPONENT C8 BETA CHAIN
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DeCS

Descriptor English:

Complement C8

Descriptor Spanish:

Complemento C8

Descriptor Portuguese:

Complemento C8

Synonyms English:

C8 Complement
Complement 8
Complement Component 8
Complement Component C8 alpha
Complement Component C8 alpha Chain
Complement Component C8 beta
Complement Component C8 beta Chain
Complement Component C8 gamma
Complement Component C8 gamma Chain
C8, Complement
Complement, C8
Component 8, Complement

Tree Number:

D12.776.124.486.274.750

Definition English:

A 150-kDa serum glycoprotein composed of three subunits with each encoded by a different gene (C8A; C8B; and C8G). This heterotrimer contains a disulfide-linked C8alpha-C8gamma heterodimer and a noncovalently associated C8beta chain. C8 is the next component to bind the C5-7 complex forming C5b-8 that binds COMPLEMENT C9 and acts as a catalyst in the polymerization of C9.

Pharmacological Action:

Immunologic Factors

History Note English:

2006 (1975)

Allowable Qualifiers English:

AD administration & dosage	AE adverse effects
AG agonists	AN analysis
AI antagonists & inhibitors	BI biosynthesis
CF cerebrospinal fluid	CS chemical synthesis
CH chemistry	CL classification
CT contraindications	DF deficiency
DE drug effects	EC economics
GE genetics	HI history
IM immunology	IP isolation & purification
ME metabolism	PK pharmacokinetics
PD pharmacology	PH physiology
PO poisoning	RE radiation effects
SE secretion	ST standards
SD supply & distribution	TU therapeutic use
TO toxicity	UL ultrastructure
UR urine

Record Number:

22139

Unique Identifier:

D003185

Occurrence in VHL:

Similar:

DeCS CID-10 SciELO LILACS LIS